CD310 (VEGFR-3) Antibody, anti-mouse, APC

01MT15808

The AFL4 monoclonal antibody reacts with mouse VEGFR-3, a member of the receptor tyrosine kinase family. This 195 kDa molecule is also known as Flt-4. During early embryogenesis all endothelial cells express VEGFR-3, while in the adult tissues, VEGFR-3 expression disappears from the vascular endothelial cells and is observed only on the lymphatic endothelium. VEGFR-3 expression is also induced upon tumor angiogenesis. VEGF-C and VEGF-D are ligands for VEGFR-3.