CD307b (FcRL2) Antibody, anti-human, Biotin, REAfinity™

01MT03978

Clone REA474 recognizes the human CD307b antigen, a single-pass type I membrane protein, which is also known as Fc receptor-like protein 2 (FcRL2) or immunoglobulin receptor translocation-associated protein 4 (IRTA4). CD307b is a protein with immunomodulatory potential that is preferentially expressed by memory B cells in humans. It has two consensus ITIMs in addition to a putative ITAM sequence in its cytoplasmic domain. Coligation of CD307b with the B cell receptor (BCR) leads to tyrosine phosphorylation of its ITIM motifs and subsequent Src homology region 2 domain-containing phosphatase-1