CD282 (TLR2) Antibody, anti-human/mouse, pure-functional grade, REAfinity™

01MT01102

Clone REA109 recognises human and mouse CD282, also known as toll-like receptor 2 (TLR2). TLRs are the host pattern recognition receptors involved in recognising pathogen associated and certain tissue damage indicating molecules. They are type 1 transmembrane proteins with extracellular leucine-rich repeats and intracellular toll/IL-1 receptor domains. TLR2 is a plasma membrane associated TLR and recognizes various structurally diverse molecules including peptidoglycans (PG), lipopeptides and lipoproteins moieties in Gram+ and Gram– bacteria, lipoteichoic acid (LTA) in Gram+ bacteria, lipoarab