CD279 (PD1) Antibody, anti-mouse, APC

01MT14170

CD279 (PD1) is a 55 kDa member of the Ig superfamily expressed mainly on activated T and B lymphocytes. Expression is induced on activated myeloid cells as well. CD279 (PD1) is thought to be involved in lymphocyte clonal selection and plays a key role in peripheral tolerance and autoimmune disease in mice. The ligands of CD279 (PD1), PD-L1 (B7-H1) and PD-L2 (B7-DC), belong to the B7 immunoglobulin superfamily. Clone HA2-7B1 has been used to block the binding of PD1 to its ligands.