CD230 (PrP) Antibody, anti-human, APC, REAfinity™

01MT01852

Clone REA203 recognizes CD230, commonly known as the prion protein (PrP). The normal cellular PrP (PrPc) is a ubiquitously expressed glycosylphosphatidyl-inositol (GPI) anchored protein. Though the main function of PrPc remains unknown, it has been suggested that PrPc may play a role in copper regulation, antioxidant activity, intracellular signaling. PrPsc is the conformational isoform of PrPc with similar primary sequence but different tertiary structure and is associated with neurodegenerative diseases such as Creutzfeldt-Jakob disease in humans, bovine spongiform encephalopathy, and scrap