CD226 (DNAM-1) Antibody, anti-human, APC

01MT14641

Clone DX11 recognizes CD226 (DNAM-1), a 65 kDa transmembrane glycoprotein expressed on T cells, natural killer (NK) cells, platelets, monocytes, and a subset of B cells. It is also expressed by a subset of CD3+ thymocytes. The surface association of CD226 (DNAM-1) with LFA-1 on NK cells and T cells permits the transduction of cytolytic signals upon binding of CD226 (DNAM-1) to its ligands CD155 (PVR) and CD112 (Nectin-2).