CD22 Antibody, anti-mouse, APC, REAfinity™

01MT12569

Clone REA1187 recognizes the 150 kDa B cell–restricted glycoprotein CD22 on mice strains having the Lyb-8.2 alloantigen, e.g., A, BALB/c, CBA, C3H/He, C57BL, C57L, C58, SJL, and SWR. Lyb-8.2 is expressed at mature levels on all B cell subsets. In bone marrow, CD22 is not detectable on pro–B cells, pre–B cells, and emerging IgM+ B cells. CD22 plays a strong role in cell interactions and B cell activation. Additional information: Clone REA1187 displays negligible binding to Fc receptors.