CD208 (DC-LAMP) Antibody, anti-human, APC, REAfinity™

01MT12382

Clone REA295 recognizes the CD208 antigen, a single-pass type I intracellular protein also known as lysosome-associated membrane glycoprotein 3 (LAMP-3) or DC-lysosome–associated membrane glycoprotein (DC-LAMP). CD208 was first cloned as a gene specifically expressed in lung tissues and found to be overexpressed in primary cancers of the esophagus, colon, fallopian tube, ovary, breast, and liver, although its expression was barely detectable in the corresponding normal tissues. It is almost exclusively expressed by mature dendritic cells (DCs). Expression can be induced in CD34+ derived dendri