CD205 (DEC205) Antibody, anti-mouse, PE, REAfinity™

01MT07273

Clone REA817 recognizes the mouse CD205 antigen, a 205 kDa integral membrane glycoprotein also known as DEC205 (dendritic and epithelial cells, 205 kDa). This membrane protein acts as an endocytic receptor and thereby mediates efficient processing and presentation of antigens in vivo, leading to the induction of T cell immunity or tolerance. CD205 is expressed at high levels on mouse dendritic cells (DCs) in the skin (Langerhans cells), on DCs residing in the T cell areas of peripheral lymphoid organs, and on DCs generated in vitro from bone marrow progenitors. To a much lower extent, CD205 is