CD1c (BDCA-1) Antibody, anti-human, Biotin, REAfinity™

01MT05776

Clone REA694 recognizes the human CD1c antigen, also known as BDCA-1. CD1c is expressed on a major subpopulation of human myeloid dendritic cells (about 0.3% of blood leukocytes). Blood CD1c (BDCA-1)+ myeloid dendritic cells are CD11chigh, CD123low, CD4+, Lin–, CD45RO+, CD2+, CD16–, CD141 (BDCA-3)low, CD303 (BDCA-2)–, and CD304 (BDCA-4/Neuropilin-1)–. They express myeloid markers (CD13, CD33) as well as Fc receptors (CD32, CD64, FcεRI) and are of monocytoid appearance. A minor proportion of CD1c (BDCA-1)+ myeloid dendritic cells expresses CD14 and CD11b. In blood, CD1c (BDCA-1) is also express