CD186 (CXCR6) Antibody, anti-human, PE, REAfinity™

01MT00954

Clone REA458 recognizes the human CD186 antigen, a multi-pass membrane protein which is also known as C-X-C chemokine receptor type 6 (CXCR6), STRL33, or bonzo. CD186 is expressed on a subset of type 1 polarized peripheral blood CD4+ and CD8+ T cells, γδ T cells, natural killer T cells, natural killer cells, monocytes, and B cells. It is induced in activated peripheral blood lymphocytes. The ligand of CD186 is the chemokine CXCL16. CD186 is used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1.Additional information: Clone REA458 displays negligible binding to Fc receptors.