CD180 (RP105) Antibody, anti-human, FITC

01MT16062

The monoclonal antibody MHR73-11 recognizes human CD180, also known as RP105, which is a 105 kDa type 1 transmembrane protein of the toll-like receptor (TLR) family. The extracellular domain of CD180 is associated with MD-1, which forms the cell surface complex RP105/MD-1. Together with TLR4, it mediates B cell recognition and signaling of LPS. CD180 is expressed on mature B cells in mantle zones, on monocytes, macrophages, and dendritic cells.