CD158a/h (KIR2DL1/DS1) Antibody, anti-human, VioBlue®

01MT14752

Clone 11PB6, also referred to as EB6, recognizes CD158a (KIR2DL1) and CD158h (KIR2DS1), two members of the killer immunoglobulin-like receptor (KIR) family expressed on CD56dimCD16+ natural killer (NK) cells and CD8+ T cells. Findings also showed reactivity of 11PB6 with KIR2DL3*005.CD158a (KIR2DL1) is involved in the transduction of an inhibitory signal whereas CD158h (KIR2DS1) is an activating receptor. The ligands of CD158a (KIR2DL1) are HLA-Cw4 and related molecules.