CD140b pY857 Antibody, anti-mouse, APC, REAfinity™

01MT04922

Clone REA628 recognizes the mouse CD140b antigen phosphorylated at tyrosine 857 (pY857). CD140b is a single-pass type I membrane protein also known as platelet-derived growth factor receptor beta (PDGFR-beta). PDGFR is composed of PDGFRα (CD140a) and/or PDGFRβ (CD140b) molecules. CD140b is broadly expressed in embryonic tissue and in cells of mesodermal origin, in adult tissue as fibroblasts, smooth muscle cells, glial cells, and chondrocytes. It is a tyrosine-protein kinase and receptor dimerization and transphosphorylation at tyrosine residues activates the intracellular kinase activity. CD1