CD137 Antibody, anti-human, APC

01MT18347

This antibody recognizes the CD137 (4-1BB) antigen, a 30 kDa glycoprotein of the tumor necrosis factor (TNF) receptor superfamily. CD137 is mainly expressed on activated CD4+ and CD8+ T cells, activated B cells, and natural killer cells, but can also be found on resting monocytes and dendritic cells.As a costimulatory molecule it is involved in the activation and survival of CD4+ or CD8+ T cells, and NK cells. CD137 has been described to be a suitable marker for antigen-specific activation of human CD8+ T cells, as it is not expressed on resting CD8+ T cells and its expression is reliably indu