CD134 (OX40) Antibody, anti-mouse, APC

01MT15908

The CD134 antigen, also known as OX40 receptor, is a 50 kDa type I membrane glycoprotein of the TNF/NGF receptor superfamily. It is expressed on activated mouse T cells and B cells. The OX40 receptor binds to the OX40 ligand (CD252) to provide a costimulatory signal which is independent of CD28. The OX-86 monoclonal antibody does not block this interaction and is reported to provide costimulation signals to T cells.