抗人 CD134 (OX40) 抗体（APC 标记，REAfinity™）

01MT00090

Clone REA621 recognizes the CD134 (OX40) antigen, a member of the tumor necrosis factor/nerve growth factor receptor (TNFR/NGFR) family. CD134 is a 50 kDa type I membrane glycoprotein expressed by activated T lymphocytes. The interaction of CD134 with OX40L has been implicated in T cell–dependent humoral response, regulation of primary T cell expansion, survival of T cells, size of the memory T cell pool, and regulation of tolerance in the CD4+ T cell compartment. It is reported, that CD134 activates NF-κB through its interaction with adaptor proteins TRAF2 and TRAF5.Additional information: Cl