CD127 Antibody, anti-mouse, APC

01MT15253

The antibody clone A7R 34 reacts with CD127, also known as interleukin 7 receptor α chain (IL-7Rα). Mouse CD127 is a 60–90 kDa type I transmembrane glycoprotein. It is a component of the high affinity IL-7 receptor (IL-7R) and the receptor for thymic stromal lymphopoietin (TSLP). CD127 is expressed on immature B cells, CD4-CD8-, CD4+, and CD8+ thymocytes, naive and memory T cells, thymic NK cells, and bone marrow stromal cells. Upon activation of naive T cells, CD127 expression is down-regulated. Re-expression of CD127 identifies the effector cells that will differentiate into memory T cells.