CD124 (IL-4Rα) Antibody, anti-mouse, Biotin, REAfinity™

01MT03570

Clone REA235 recognizes the CD124 antigen, a 140 kDa transmembrane glycoprotein which is also known as interleukin-4 receptor subunit alpha (IL-4Rα). CD124 is expressed on both B and T lymphocytes, and on cells of several other hematopoietic lineages, including mast cell, macrophage, and undifferentiated hematopoietic cell lines. CD124 is a receptor for both IL-4 and IL-13. The functional IL-4 receptor is formed by initial binding of IL-4 to IL-4R. Subsequent recruitment to the complex of the common γ chain, in immune cells, creates a type I receptor and, in non-immune cells, of CD213a1 (IL-13