CD120a (TNF-RI) Antibody, anti-human, APC, REAfinity™

01MT03654

Clone REA252 recognizes the extracellular part of the membrane-bound and soluble form of the CD120a antigen, a 55 kDa type I transmembrane glycoprotein also known as tumor necrosis factor receptor type I (TNF-RI) or p55. CD120a belongs to the TNF receptor superfamily and is mainly expressed by monocytes, macrophages, and neutrophils. It is also expressed by a variety of cell lines, tumor cells, and normal cell types including T cells, endothelial cells, hepatocytes, chondrocytes, and fibroblasts. Binding of TNF-α to its main receptor CD120a triggers signaling which is extremely complex, leadin