CD112 Antibody, anti-human, APC, REAfinity™

01MT12757

Clone REA1195 recognizes the human CD112 antigen, a Single-pass type I membrane protein which is also known as Nectin-2, Herpesvirus entry mediator B (HveB) or Poliovirus receptor-related protein 2 (PRR2). Nectins are Ca2+-independent cell adhesion molecules that consist of 4 members: CD111 (Nectin-1), CD112 (Nectin-2), CD113 (Nectin-3), and Nectin-4. CD112 is one of the plasma membrane components of adherens junctions and is widely expressed in human tissues, including hematopoietic cells. It is also over-expressed in various cancers, e.g. breast and ovarian cancers. It has been reported to r