CD107b Antibody, anti-human, APC, REAfinity™

01MT11136

Clone REA1073 recognizes the human CD107b, also known as lysosomal-associated membrane protein-2 (LAMP-2), which is a 120 kDa highly glycosylated type I transmembrane protein. It is widely located in lysosomal/endosomal membranes in a high variety of cell types and also expressed on degranulating T cells, activated platelets, and some tumor cell lines. CD107b is involved in cell adhesion and cellular homeostasis, including autophagocytosis and antigen presentation as well as in tumor cell metastasis.Additional information: Clone REA1073 displays negligible binding to Fc receptors.