CD105 Antibody, anti-mouse, APC, REAfinity™

01MT11044

Clone REA1058 recognizes the mouse CD105 antigen, also known as endoglin. CD105 is a proliferation-associated and hypoxia-inducible protein, abundantly expressed in angiogenic endothelial cells. In mouse bone marrow, CD105 is also expressed on a population of Sca-1+ hematopoietic stem cells (HSCs). This population has a long-term repopulating (LTR) capacity and is therefore termed LTR-HSCs. Furthermore, on liver sinusoidal endothelial cells (LSEC), CD105 is co-expressed with CD146 (LSEC).Additional information: Clone REA1058 displays negligible binding to Fc receptors.