CD104 (Integrin β4) Antibody, anti-human, PE-Vio® 770, REAfinity™

01MT01884

Clone REA236 recognizes CD104, which is also known as integrin β4. Integrins are a family of type I transmembrane heterodimeric glycoprotein receptors and exist as non-covalently bound α and β subunits. CD104 interacts with α6 integrin and serves as receptor for laminin and component of hemidesmosomes. Expression of α6β4 integrin is found in the basal aspect of stratified epithelia such as epidermis, stratified squamous epithelium of squamous mucosa, urothelium, and certain tumor cells. Additional information: Clone REA236 displays negligible binding to Fc receptors.