CCL5 (RANTES) Antibody, anti-human, APC, REAfinity™

01MT11932

Clone REA346 recognizes the human C-C motif chemokine 5 (CCL5) antigen, a 8 kDa protein also known as RANTES (regulated on activation, normal T cell expressed and secreted). CCL5 belongs to the C-C chemokine family and is a target gene of NF-κB activity. It is expressed by T lymphocytes, macrophages, platelets, synovial fibroblasts, tubular epithelium, and certain types of tumor cells. NF-κB activation by different stimuli such as CD40L or interleukin 15 (IL-15) induces CCL5 production. CCL5 plays an active role in recruiting a variety of leukocytes into inflammatory sites including T cells, m