Cadherin-6 Antibody, anti-human, PE, REAfinity™

01MT08159

Clone REA846 recognizes the human cadherin-6 antigen, a type I membrane-associated glycoprotein also known as K-cadherin or KCAD, which is a member of the cadherin superfamily. Cadherin-6 is found in a high level in kidney, brain, and cerebellum. It is also expressed in renal and ovariancarcinoma and in a low level in lung, pancreas, gastric mucosa, and cytotrophoblasts. Cadherins are involved in cell adhesion, forming adherens junctions. This is mediated by extracellular domains of cadherins, whereas the intracellular cytoplasmic tail associates with different adaptor and signaling proteins.A