c-Rel Antibody, anti-mouse, APC, REAfinity™

01MT03581

Clone REA397 recognizes the mouse c-Rel antigen, a 65 kDa member of the NF-κB family of eukaryotic transcription factors, which also includes the proteins RelA (p65), RelB, NF-κB1 (p105/p50), and NF-κB2 (p100/p52). NF-κB transcription factors can form various homo- and heterodimers possessing unique specificities in regulating target gene expression. While RelA-containing dimers are present in most cell types, c-Rel complexes are predominately found in cells of hematopoietic origin. In T cell lymphocytes, certain genes essential for immune function such as interleukin 2 (IL-2) and FoxP3 are di