抗 TRIM54 磁珠
02AB00135
Tripartite motif-containing protein 54 (TRIM54) is a member of the TRIM protein family, characterized by its tripartite motif consisting of a RING finger domain, B-box, and coiled-coil regions. It shares significant similarity with other RING finger proteins such as MURF1 and MURF2. TRIM54 plays a crucial role in regulating microtubule dynamics and myogenic differentiation. Dysregulation of TRIM54 has been implicated in various diseases, including Charcot-Marie-Tooth disease, a type of peripheral neuropathy, and gastric cancer. TRIM54 has also been associated with other malignancies, suggesting its potential as a biomarker for cancer diagnosis and prognosis. Additionally, TRIM54 is involved in the regulation of muscle-specific proteins and may contribute to the pathogenesis of muscular disorders.
| 规格 | 起售价 |
|---|---|
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技术参数
- 宿主
- Mouse
- 靶点基因名
- TRIM54
- 基因别名
- MURF; MURF3; RNF30
- 蛋白别名
- tripartite motif containing 54; TRIM54
- UniProt
- Q9BYV2
- 物种
- Human, Mouse
- 应用
- IP
产品详情
- 靶点名称
- TRIM54
- 蛋白名称
- tripartite motif containing 54
- 蛋白别名
- Tripartite motif-containing protein 54; Muscle-specific RING finger protein; MuRF; Muscle-specific RING finger protein 3; MuRF-3; MuRF3; RING finger protein 30
- 靶点基因名
- TRIM54
- 基因别名
- MURF; MURF3; RNF30
- UniProt
- Q9BYV2
- 来源物种
- Homo sapiens (Human)
- 宿主物种
- Mouse
- 物种反应性
- Human, Mouse
- 克隆性
- Monoclonal
- 亚型
- IgG1
- 配方
- Supplied as solution in phosphate buffered saline containing 0.1% BSA and 0.02% sodium azide
- 剂型
- Subject to solid-liquid separation upon standing; Mix thoroughly to ensure a consistent, homogeneous
免疫原核心序列
LLQALAREQEEKLQRVRGLIRQYGDHLEASSKLVESAIQSMEEPQMALYLQQAKELINKVGAMSKVELAGRPEPGYESMEQFTVRVEHVAEMLRTIDFQPGASGEEEEVAPDGEEGSAGP
| 应用 | 推荐稀释比 | 备注 |
|---|---|---|
| IP | — | 50-100 μL/200 μg cell lysate |
背景介绍
Tripartite motif-containing protein 54 (TRIM54) is a member of the TRIM protein family, characterized by its tripartite motif consisting of a RING finger domain, B-box, and coiled-coil regions. It shares significant similarity with other RING finger proteins such as MURF1 and MURF2. TRIM54 plays a crucial role in regulating microtubule dynamics and myogenic differentiation. Dysregulation of TRIM54 has been implicated in various diseases, including Charcot-Marie-Tooth disease, a type of peripheral neuropathy, and gastric cancer. TRIM54 has also been associated with other malignancies, suggesting its potential as a biomarker for cancer diagnosis and prognosis. Additionally, TRIM54 is involved in the regulation of muscle-specific proteins and may contribute to the pathogenesis of muscular disorders.