Anti-TCRα/β-APC

01MT18398

REA652 recognizes the human α/β T cell receptor (TCR). The T cell receptor is a heterodimer composed of two transmembrane glycoprotein chains, α and β. In 95% of T cells the TCR consists of an α and β chain, whereas in 5% of T cells it has γ and δ chains. α and β chains are members of the Ig superfamily and consist of a constant and a polymorphic variable region. The variable region of the TCRα/β is involved in recognition of antigenic peptides presented by the MHC complex of antigen-presenting cells.Additional information: Clone REA652 displays negligible binding to Fc receptors.