ADAM15 Antibody, anti-human, APC, REAfinity™

01MT05220

Clone REA650 recognizes the human ADAM15 antigen, a transmembrane protein, which contains disintegrin and metalloprotease domains. ADAM15 belongs to the membrane linked metalloproteinase family (ADAM), which has gelatinolytic and collagenolytic activities. It has several functions, for example, it is involved in wound healing process and in glomerular cell migration. Furthermore ADAM15 suppresses beta-1 integrins-mediated cell adhesion and migration of smooth muscle cells.Expression of ADAM-15 is found in airway smooth muscle, glomerular mesangial cells, colon, small testine, and chondrocytes.